Hi Everyone,
I hope someone can help as I have run out of ideas.
My father in laws pc ( An Acer Aspire AX1301 ) prompted him to update to Windows 10. During the upgrade the PC turned off and since then it has been unable to boot. Given that I am the only one in the extended family with any IT experience I have been tasked to resolve this 
When booting now we see:
Nvidia Boot Agent 249.0542
PXE-E61: Media Test failure, check cable
PXE-M0F: Exiting NVIDIA Boot Agent.
DISK BOOT FAILURE, INSERT SYSTEM DISK AND PRESS ENTER
I have since downloaded and tried to start fresh USB installs of Windows 10,8 & 7 but in each case the install gets to the point where I choose the location of the install. At this point there is no Hard Disk listed and only an option to Load Driver.
The issue here is that the HD is a WD Blue 320GB and they do not appear to supply any drivers for this HD.
After all this, I did think that the drive was maybe busted, so I took out and put into an external enclosure. Strangely though the HD is still completely accessible with a Windows & Windows.old directory structure. If its worth anything the old Windows version appears to be 7.6 7601.19161.
I have checked all internal cables and these are fine, I don't think that the install could have done anything to the BIOS that could result in this.
Any feedback or suggestions will be appreciated.
David